The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems that cost at least $600,000. The maximum award is $2,000,000. Types of instruments supported include, but are not limited to: X-ray diffraction systems, nuclear magnetic resonance (NMR) and mass spectrometers, DNA and protein sequencers, biosensors, electron and confocal microscopes, cell-sorters, and biomedical imagers.
There is no limit on the number of applications an institution may submit provided the applications are for different types of equipment. While there is no limit on number of applicants to this program, an internal screening will be held to ensure this criterion is met.
There is no restriction on the number of applications an institution can submit to the Shared Instrumentation Grant (SIG) and/or HEI Programs each year provided the applications request different types of equipment. Concurrent SIG and/or HEI applications for the same instrument (or the same type of instrument with added special accessories to meet the HEI budget requirement) are not allowed, in general. If two or more S10 (either SIG or HEI) applications are submitted for similar equipment from the same institution, documentation from a high level institutional official must be provided stating that this is not an unintended duplication, but part of a campus wide instrumentation plan. Applicants are advised to discuss with the HEI Scientific/Research Contact (see Section VII) potential duplicates before submitting two applications for the same type of instrument. A single application requesting more than one type of instrument (for example, a mass spectrometer and a confocal microscope) is not appropriate for this FOA. A Major User group composed of three individuals who have substantial need for the instrument must be identified. Each member of this group must be a PD/PI on a distinct NIH-funded research grant or cooperative agreement award in an area of basic, translational, or clinical research. (The requirement is one award per investigator, with more awards per investigator allowed. An award given to multi-PDs/PIs is counted only once towards the fulfillment of this requirement.) PDs/PIs on NIH training or fellowship grants (e.g., T and F mechanisms) and other non-research grants are not eligible to be Major Users. Once the eligibility requirement has been met, additional users with active research awards from NIH or other sources may be added as Major or Minor Users. Investigators with funding from sources such as other Federal agencies (e.g., NSF, DoE, DoD), private foundations or academic institutions can be added as Major Users provided they are engaged in basic, translational or clinical research and can demonstrate a substantial need for the instrument once the requirement of at least three NIH-funded Major Users has been met. Major Users can be researchers from the same department or from several departments, divisions or schools at the applicant institution, or from nearby or regional institutions. In certain circumstances, as technology dictates, Major Users may come from distant institutions, but they must demonstrate the need for and regular access to the instrument.
RESPONSE TO OSP: March 16, 2016